| Sucralfate |
Al8(OH)16(C12H14O35S8) [Al(OH)3]x [H2O]y Sucralfate is the basic aluminium salt of sucrose octasulfate (SOS). The therapeutic effect of Sucralfate in gastric complaints is based on an increase in the protective mechanisms of the mucous membranes in the stomach and duodenum against exogenous and endogenous aggressors. The cytoprotective action of Sucralfate includes the neutralization of acid, the selective formation of a protective layer over eroded surface areas, specific protection of lesions and adsorption of pepsin and bile acids, resulting in inhibition of peptic activity.
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Sucralfate Powder S 215, S 225 and S 235 Sucralfate S 215 powder is suitable for use in tablet formulations. Sucralfate S225 is a milled powder ideal for use in soft tablet and candy formulations or for powder mixtures intended for resuspending (powder sachets). Sucralfate S 235 is available for direct compressible tablet formulations. | Type | Assay Al | Assay SOS | Density (tapped) | d50 | Pharmacopoeia  | | S 215 | 15,5 - 18,5 [%]
16,5 - 18,5 [%] | 30,0 - 38,0 [%]
30,0 - 36,0 [%] | 0,55 - 0,75 [g/ml] | 30 - 45 [µm] | USP PhEur | | S 225 | 15,5 - 18,5 [%] 16,5 - 18,5 [%] | 30,0 - 38,0 [%] 30,0 - 36,0 [%] | 0,30 - 0,48 [g/ml] | 3 - 5 [µm] | USP PhEur | | S 235 | 15,5 - 18,5 [%] 16,5 - 18,5 [%] | 30,0 - 38,0 [%] 30,0 - 36,0 [%] | 0,6 - 0,8 [g/ml] | 90 - 130 [µm] | USP PhEur | |
HTML Source Editor Sucralfate Suspension S 611 Sucralfate S611 is a suspension with an active content of 30% Sucralfate. It is ideal for use in liquid antacid formulations. | Type | Assay | Assay SOS | d50 | Pharmacopoeia | | S611 | 4,7 - 6,0 [%] | 8,3 - 13,4 [%] | 4 - 6 µm | USP | |
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